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Isoform-specific targeting of ROCK proteins in immune cells

Alexandra Zanin-Zhorov, Ryan Flynn, Samuel D Waksal and Bruce R Blazar. Small GTPases 2016; 1-6. Article

Review article related to the above Blood publication summarizing the effects of ROCK2 inhibition in T cells, including  Kadmon research on ROCK2 plasticity and macrophage polarization and relevance to autoimmunity and GVHD