Scientific Publications

Science

Publications


  • Cutting Edge: Selective Oral ROCK2 Inhibitor Reduces Clinical Scores in Patients with Psoriasis Vulgaris and Normalizes Skin Pathology via Concurrent Regulation of IL-17 and IL-10. The Journal of Immunology. .
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  • ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings. Sci. Signal. .
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  • Isoform-specific targeting of ROCK proteins in immune cells. Small GTPases. .
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  • Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism. Blood. .
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  • ROCKing cytokine secretion balance in human T cells. Cytokine. .
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  • Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism. PNAS. .
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  • Selective ROCK2 inhibition in focal cerebral ischemia. ANA. .
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